Besties is a television game show where best friends answer questions about each other and the best friends who get the most points win a cruise, hosted by Chuck Berost. Bugs and Daffy are joined and competed against Mac and Tosh, in the debut episode "Best Friends." Bugs and Daffy lost 700-600 to Mac and Tosh, who won the cruise, after Daffy didn't know that Bugs' catchphrase was "What's up doc?".
When you answer a question wrong, something gets dumped on you, such as fish or get ejected.
Besties is said to be a parody of the real life show, The Price is Right.